Streptokinase: about of a thrombolytic patented in Cuba
نویسندگان
چکیده
A failure of hemostasis of the organism could cause the formation of clots inside the circulatory system, causing disorders of the system that lead to such processes like the stroke or myocardial infarction. The treatment of these pathologies could require the application of thrombolytic agents like the urokinase (Uk), the tissue type plasminogen activator (tPA) or the streptokinase (Sk). This review approaches the position of Sk as clinically important and with good relationship cost-effectiveness in the treatment of the thrombolytic processes. The aspects discussed include mode of action, structure and relationship structure-function, structural modifications that could improve their function, sources of obtaining, recombinant streptokinase, production and purification of this protein and their current position in the market.
منابع مشابه
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